New targeted therapies are revolutionising cancer treatment – they can turn cancer into a chronic disease. However, they do not work for everyone and some patients, who have initially responded to these novel therapies, become resistant and their disease progresses. There are a huge number of novel targeted therapies in pre-clinical and early clinical trials.

Patient with resistant disease often seek out these trials as a means to stay alive and some patients’ lives have been saved by finding information about such trials on the Internet. Unfortunately, information about clinical trials in progress is often shrouded in a veil of secrecy, and patients find it hard to locate trials that address their specific condition.

Here is a list of Clinical Trials Databases:

Sarcoma Trial Databases

• GIST Support International: Current Trials for GIST Cancer
• British Sarcoma Group Database with sarcoma studies open in the UK:
  http://www.britishsarcomagroup.org.uk/#/uk-clinical-trials/4551919396
• Database of clinical trials in the UK maintained by Cancer Research UK: Cancer Help UK
• European Phase 3 Trials: EORTC
• GIST trials at the clinicaltrials.gov website (USA)
• Sarcoma Trials at the clinicaltrials.gov website (USA)
• Life Raft Group GIST Clinical Trials Database (USA): LRG GIST Clinical Trials List

General Clinical Trial Databases and Registries

• EU Clinical Trials Register (EU-CTR) - https://www.clinicaltrialsregister.eu/
• European Medicines Agency (EMEA) - European CTs database (EudraCT) - EudraPharm
• Coalition of national cancer cooperative groups - cancertrialshelp.org
• ClinicalTrials.gov (USA) - www.clinicaltrials.gov
• CancerHelp Clinical Trials Database (UK) - www.cancerhelp.org.uk/trials (database of cancer trials that are recruiting in the UK, including lay information, recruiting trials, closed trials and trial results)
• German Clinical Trial Register (DE) - www.germanctr.de
• TrialCheck.org - www.trialcheck.org
• IKC net (Netherlands) - http://www.ikcnet.nl/trials/
• NCI.gov Clinical Trials Register (USA) - http://www.cancer.gov/clinicaltrials
• Australian Cancer Trials: http://www.australiancancertrials.gov.au/

Company Trial Databases

• PhRMA Clinical Study Results Database - www.clinicalstudyresults.org
• IFPMA Clinical Trials Portal - clinicaltrials.ifpma.org
• Association of the British Pharmaceutical Industry (ABPI) - Phase III/IV Trials in UK - https://www.cmrinteract.com/clintrial/
• Novartis Clinical Trials - www.novartisclinicaltrials.com/
• Roche Trials - http://www.roche-trials.com
• EmergingMed - www.emergingmed.com